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Top 3 Wellness Essentials: Fish Oil, Probiotics, + Collagen

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While multivitamins dominate total sales within the dietary supplement marketplace, three wellness essentials stand out and hold significant market share: fish oil, probiotics, and collagen. These three wellness essentials share a common feature—each addresses an underlying, foundational aspect in building health within the human body.

This article aims to explain how each of these widely popular categories of supplements works to promote health and why they have become so essential to so many people.

Fish Oil

Why Supplement With Fish Oil?

A significant advancement in nutritional medicine is the production of highly concentrated fish oil supplements rich in long-chain omega-3 fatty acids, free from harmful compounds (lipid peroxides, heavy metals, environmental contaminants, etc.). Pharmaceutical-grade fish oil concentrates offer a superior alternative to consuming fish due to issues like mercury contamination.

The majority of the population consumes excessive omega-6 oils from meats, dairy, and vegetable oils, leading to a deficiency in omega-3 oils. This is linked to higher risks of chronic health issues. Long-chain omega-3 fatty acids like EPA and DHA are vital for good health.

Fish Oil Benefits

Long-chain omega-3 fatty acids play a crucial role in cellular membranes and inflammation control. 

A diet lacking EPA and DHA alters cell membranes, affecting water retention and nutrient absorption. This dysfunction hinders cell communication, regulation by hormones, and overall function, contributing to chronic diseases. Restoring omega-3 levels in cell membranes through fish oil supplementation offers significant health benefits.[1]

Long-chain omega-3 fatty acids transform into regulatory compounds that help with inflammation and cellular repair, promoting overall health by enhancing various cellular mechanisms. These benefits affect every cell and system in the body, making fish oils helpful in a long list of health conditions, as confirmed in over 1,000 double-blind, controlled trials in humans. 

Based on substantial evidence, fish oil supplements with EPA+DHA offer health benefits when red blood cell concentration exceeds 8%. Levels below 4% pose a high risk for 60+ health conditions, like heart disease and dementia. Studies show vegans, vegetarians, and some omnivores who do not supplement with fish oil have low EPA+DHA levels, elevating the risk for health problems, especially related to inflammation and heart and brain health.[1]

How to Choose a Fish Oil Supplement

When choosing a fish oil supplement, opt for a trusted brand with strict quality control to ensure it's free from heavy metals, pesticides, damaged fats, and other contaminants. The recommended daily EPA+DHA dosage for general health is 1,000 mg. Remember, it's not 1,000 mg of fish oil but 1,000 mg of total omega-3 fatty acids you need. For extra support, consider a daily dosage of up to 3,000 mg of omega-3 fatty acids.

Summary

Fish oil supplements are a valuable source of omega-3 fatty acids, crucial for cellular health and inflammation control. They offer numerous benefits, aiding in various health conditions. Choose a reputable brand with high-quality standards to reap the benefits without harmful contaminants. Aim for a daily intake of 1,000 mg of EPA+DHA for general health, with potential benefits of up to 3,000 mg daily.

Probiotics

What Are Probiotics?

Probiotics are the beneficial bacteria, yeast, and other microorganisms that inhabit the human intestinal tract. Manufacturers of probiotics typically provide safely freeze-dried live forms of many of these beneficial bacteria so that they can be put in capsules, liquids, or food and brought back to life in the human intestinal tract.

Probiotic Foods

Probiotics are also found in fermented foods such as yogurt, aged and raw cheeses, kefir, kimchi, sauerkraut, and miso. The specific microorganisms found in these products will vary but usually include Lactobacilli and Bifidobacteria, which are the major probiotics found in dietary supplements.

Probiotic Benefits

Probiotics can aid in supporting the health of our microbiome, which consists of genetic material from the microbes in our body. The human body hosts a vast number of microbiota - bacteria, viruses, and fungi. An estimated 100 trillion microbial cells from around 1,000 species coexist in a symbiotic relationship within or on us.

The human intestinal microbiome plays an integral role in our overall health. Many people look to probiotic supplements to improve the intestinal microbiome and thus improve health. This use of probiotics is supported by significant clinical research with over 1,000 double-blind, placebo-controlled studies. 

Much of the research has focused on the use of probiotics to promote gastrointestinal health and support immune function, but clinical research also supports the use of probiotics for supporting many other health goals.[7,8]

Probiotics enhance the gut environment, making it less desirable for harmful microbes. Some probiotic strains can stick to intestinal cells, acting as barriers against unwanted bacteria and yeast.[9]

Probiotics can boost the immune response. For instance, specific bacteria can enhance IgA secretion, which defends our intestines against infections. Clinical studies have demonstrated probiotics' ability to activate essential immune cells like natural killer cells and macrophages.[10]

Probiotics are well-documented for treating various gastrointestinal issues, especially in preventing and recovering from diarrhea linked to irritable bowel syndrome, infectious causes, and antibiotics. Clinical trials show that taking probiotics during and after antibiotics yields the best results.[9,11-15]

There is a growing list of health benefits of probiotic supplementation. For example, probiotics have been shown to support healthy cholesterol metabolism and heart health, while others have shown benefits to mood and stress, oral health, and many more health targets.[16-18]

How to Choose a Probiotic Supplement

Quality is important, as is the case with fish oils. The quality of a probiotic supplement depends on two main factors: 

  1. Characteristics of the probiotic strain
  2. Adequate viability  

Strains of bacteria can be likened to different breeds of dogs. Just as there is a great diversity in size, shape, strength, and other physical characteristics in different breeds of dogs, there are different aspects with bacteria, even if they are both from the same strain. 

Using probiotic supplements with defined strains that have been tested in human clinical trials is recommended.[19] 

The dosage of probiotic supplements is often based on the number of live organisms present in the product, but it depends on the probiotic being used. If a live probiotic strain is being used, it is important to use products that list the number of live organisms at expiration versus the time of manufacture (which means nothing). 

Successful results are often attained by taking between 5 billion and 20 billion viable organisms daily. Higher dosages may be necessary in certain cases.

Summary

Probiotics, or beneficial bacteria and microorganisms in our intestines, can be found in supplements and fermented foods. Probiotics support gut health, boost immunity, and aid in various health issues like gastrointestinal problems. Choose a quality supplement with tested strains for optimal benefits.

Collagen

What Is Collagen? What Does It Do?

Collagen, the body's most abundant protein, holds cells and structures together. Together with hyaluronic acid and elastin, it forms the "intracellular cement" binding body cells. Collagen is vital in connective tissues like tendons, ligaments, and the skin's support layer, the dermis. Our largest organ is the skin, which is 70% collagen and connective tissue.

Bone is rich in collagen, making up 30-40% of its composition. Collagen acts as the structural matrix for bone mineralization, akin to 2X4s in a house frame. Reduced bone collagen levels contribute to lower density with age, particularly in women, affecting mineral binding sites and bone strength. If collagen levels are low, the bone becomes more brittle, and fracture risk increases dramatically.

Collagen supplements help the body build its own collagen structures more efficiently. Collagen peptides are easier to absorb and offer health benefits. These supplements come from cows, chickens, pigs, and fish.

Collagen Benefits

Clinical studies reveal significant benefits of collagen peptide supplementation in enhancing joint, skin, hair, and nail health. While most noticeable in those over 40, these supplements offer benefits at any age.[20-24] 

The benefits are more noticeable in those over 40 because fibroblasts, which create collagen and other connective tissues, decline sharply as we age. This leads to skin wrinkling and sagging due to collagen loss, joint stiffness, and inflammation. Collagen peptide supplementation can aid by offering collagen's building blocks for collagen synthesis.

Collagen peptides provide overall body support, with a notable use as a "beauty from within" supplement. Studies show they can help maintain skin elasticity and hydration, potentially reducing signs of skin aging and smoothing fine lines, especially when taken consistently for at least six months. Studies typically used a daily dosage of 5 grams.[21-23] 

Summary

Collagen, the body's key protein, is crucial for skin and bones. Supplements aid in collagen synthesis, benefiting joint and skin health. Studies show improved skin elasticity and hydration with consistent intake.

Takeaway

Discover the top wellness essentials in the supplement market: fish oil for omega-3 benefits, probiotics for gut health, and collagen for skin and joints. Choose high-quality brands for optimal results!

References:

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  2. Thompson M, Hein N, Hanson C, Smith LM, Anderson-Berry A, Richter CK, Stessy Bisselou K, Kusi Appiah A, Kris-Etherton P, Skulas-Ray AC, Nordgren TM. Omega-3 Fatty Acid Intake by Age, Gender, and Pregnancy Status in the United States: National Health and Nutrition Examination Survey 2003⁻2014. Nutrients. 2019 Jan 15;11(1):177.
  3. Choi H, Kim JY, Lee KH, et al. Omega-3 fatty acids supplementation on major cardiovascular outcomes: an umbrella review of meta-analyses of observational studies and randomized controlled trials. Eur Rev Med Pharmacol Sci. 2021 Feb;25(4):2079-2092. 
  4. Gao Z, Zhang D, Yan X, Shi H, Xian X. Effects of ω-3 Polyunsaturated Fatty Acids on Coronary Atherosclerosis and Inflammation: A Systematic Review and Meta-Analysis. Front Cardiovasc Med. 2022 Jun 20;9:904250. 
  5. Calder PC. Omega-3 fatty acids and inflammatory processes: from molecules to man. Biochem Soc Trans. 2017 Oct 15;45(5):1105-1115. 
  6. Kavyani Z, Musazadeh V, Fathi S, Hossein Faghfouri A, Dehghan P, Sarmadi B. Efficacy of the omega-3 fatty acids supplementation on inflammatory biomarkers: An umbrella meta-analysis. Int Immunopharmacol. 2022 Oct;111:109104.
  7. da Silva TF, Glória RA, Americo MF, Freitas ADS, de Jesus LCL, Barroso FAL, Laguna JG, Coelho-Rocha ND, Tavares LM, le Loir Y, Jan G, Guédon É, Azevedo VAC. Unlocking the Potential of Probiotics: A Comprehensive Review on Research, Production, and Regulation of Probiotics. Probiotics Antimicrob Proteins. 2024 Mar 28. 
  8. Lee ES, Song EJ, Nam YD, Lee SY. Probiotics in human health and disease: from nutribiotics to pharmabiotics. J Microbiol. 2018;56(11):773-782.
  9. Rau S, Gregg A, Yaceczko S, Limketkai B. Prebiotics and Probiotics for Gastrointestinal Disorders. Nutrients. 2024 Mar 9;16(6):778.
  10. Miller LE, Lehtoranta L, Lehtinen MJ. Short-term probiotic supplementation enhances cellular immune function in healthy elderly: systematic review and meta-analysis of controlled studies. Nutr Res. 2019 Apr;64:1-8
  11. Yang R, Jiang J, Ouyang J, Zhao Y, Xi B. Efficacy and safety of probiotics in irritable bowel syndrome: A systematic review and meta-analysis. Clin Nutr ESPEN. 2024 Apr;60:362-372. doi: 10.1016/j.clnesp.2024.02.025. Epub 2024 Feb 29. PMID: 38479936.
  12. Miller LE, Ouwehand AC, Ibarra A. Effects of probiotic-containing products on stool frequency and intestinal transit in constipated adults: systematic review and meta-analysis of randomized controlled trials. Ann Gastroenterol. 2017;30(6):629-639.
  13. Wang F, Zhao T, Wang W, Dai Q, Ma X. Meta-analysis of the efficacy of probiotics to treat diarrhea. Medicine (Baltimore). 2022 Sep 23;101(38):e30880. 
  14. Bae JM. Prophylactic efficacy of probiotics on travelers' diarrhea: an adaptive meta-analysis of randomized controlled trials. Epidemiol Health. 2018;40:e2018043.
  15. Blaabjerg S, Artzi DM, Aabenhus R. Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients-A Systematic Review and Meta-Analysis. Antibiotics (Basel). 2017;6(4):21.
  16. Khan S, Ahmad F, Khalid N. Applications of Strain-Specific Probiotics in the Management of Cardiovascular Diseases: A Systemic Review. Mol Nutr Food Res. 2024 Mar 29:e2300675.
  17. El Dib R, Periyasamy AG, de Barros JL, et al. Probiotics for the treatment of depression and anxiety: A systematic review and meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2021 Oct;45:75-90. 
  18. Inchingolo F, Inchingolo AM, Malcangi G, et al. The Benefits of Probiotics on Oral Health: Systematic Review of the Literature. Pharmaceuticals (Basel). 2023 Sep 16;16(9):1313. 
  19. Pramanik S, Venkatraman S, Karthik P, Vaidyanathan VK. A systematic review on selection characterization and implementation of probiotics in human health. Food Sci Biotechnol. 2023 Jan 10;32(4):423-440. 
  20. Martínez-Puig D, Costa-Larrión E, Rubio-Rodríguez N, Gálvez-Martín P. Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge. Nutrients. 2023 Mar 8;15(6):1332.
  21. Kim DU, Chung HC, Choi J, Sakai Y, Lee BY. Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study. Nutrients. 2018 Jun 26;10(7):826
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